DBCO-PEG4-NHS ester

DBCO-PEG4-NHS ester

DBCO-PEG4-NHS Ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22288
    • Unit
    • Price
    • Qty
    • 50 MG
    • $165.00
    • 100 MG
    • $280.00
    • 250 MG
    • $485.00
    • 500 MG
    • $720.00

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Product Citations

  1. Dong, Y., You, F., Zhang, Y., Sun, H., Cheng, R., Zhao, S., ... & Zhong, Z. (2024). CD7 Nanobody-Based Immuno-Nanotoxin for Targeted Treatment of T-Cell Acute Lymphoblastic Leukemia. ACS Applied Nano Materials, 7(7), 7195-7202.
    https://doi.org/10.1021/acsanm.3c06253
  2. Krishnan, M. A., Alimi, O. A., Pan, T., Kuss, M., Korade, Z., Hu, G., ... & Duan, B. (2024). Engineering Neurotoxin-Functionalized Exosomes for Targeted Delivery to the Peripheral Nervous System. Pharmaceutics, 16(1), 102.
    https://www.mdpi.com/1999-4923/16/1/102
  3. Mauser, Ava, Daniel F. Quevedo, Boya Zhang, Yazmin Hernandez, Anthony Berardi, William Brown, Sophia Lee Enzyme?based Synthetic Protein Nanoparticles as Colloidal Antioxidants. Advanced Therapeutics. 2023
    https://onlinelibrary.wiley.com/doi/full/10.1002/adtp.202300007
  4. Studer, Tetiana, Daria Morina, Inga S. Shchelik, and Karl Gademann.  Biohybrid Microswimmers for Antibiotic Drug Delivery Based on a Thiol?Sensitive Release Platform. Chemistry-A European Journal. 2023
    https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.202203913