DBCO-PEG4-NHS ester
DBCO-PEG4-NHS Ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. . Please contact us for GMP-grade inquiries.

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Catalog:
BP-22288
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Name:
DBCO-PEG4-NHS ester
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Formula:
C34H39N3O10
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MW:
649.7
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CAS:
1427004-19-0
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Purity:
98%
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Solubility:
DMSO, DCM, DMF
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Shipping:
Ambient Temperature
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Availability:
In Stock
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NMR:
View
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SDS:
View
Product Citations
- Dong, Y., You, F., Zhang, Y., Sun, H., Cheng, R., Zhao, S., ... & Zhong, Z. (2024). CD7 Nanobody-Based Immuno-Nanotoxin for Targeted Treatment of T-Cell Acute Lymphoblastic Leukemia. ACS Applied Nano Materials, 7(7), 7195-7202.
https://doi.org/10.1021/acsanm.3c06253 - Krishnan, M. A., Alimi, O. A., Pan, T., Kuss, M., Korade, Z., Hu, G., ... & Duan, B. (2024). Engineering Neurotoxin-Functionalized Exosomes for Targeted Delivery to the Peripheral Nervous System. Pharmaceutics, 16(1), 102.
https://www.mdpi.com/1999-4923/16/1/102 - Mauser, Ava, Daniel F. Quevedo, Boya Zhang, Yazmin Hernandez, Anthony Berardi, William Brown, Sophia Lee Enzyme?based Synthetic Protein Nanoparticles as Colloidal Antioxidants. Advanced Therapeutics. 2023
https://onlinelibrary.wiley.com/doi/full/10.1002/adtp.202300007 - Studer, Tetiana, Daria Morina, Inga S. Shchelik, and Karl Gademann. Biohybrid Microswimmers for Antibiotic Drug Delivery Based on a Thiol?Sensitive Release Platform. Chemistry-A European Journal. 2023
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.202203913