BP Lipid 494 has been designed to be a PEG-type analog of ether lipid BP Lipid 495. The multichargeable head group consists of methylpiperazine three carbon spacer linked via a biodegradable ester linkage to three ether tails, each terminated by a free azido group for click chemistry applications or surface modification. This compound may represent a novel and functional addition for lipid nanoparticle formulations for mRNA delivery.
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