GT-11 is the first known inhibitor of dihydroceramide desaturase, an enzyme that converts dihydroceramide to ceramide, a key bioactive compound. Ceramides are crucial for cell membrane structure and various cellular processes, including signaling and apoptosis. By inhibiting this enzyme, GT-11 can impact ceramide production and associated cellular pathways. GT-11 shows potential as a cell-protective agent, with possible therapeutic uses.
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