BET Inhibitors

BET Inhibitors

Bromodomain and Extra-Terminal motif (BET) inhibitors are a class of small molecule drugs that reversibly bind the bromodomains of BET proteins BRD2, BRD3, BRD4, and BRDT. These BET inhibitors prevent protein-protein interaction between BET proteins and acetylated histones and transcription factors. Dysregulated bromodomains of BET proteins are frequently found in cancer showing aberrant chromatin remodeling and gene expression.

Catalog Product Name Structure M.W. Purity Pricing
(+)JQ-1
BP-21590(+)JQ-1Molecular structure of the compound: (+)JQ-1457Pricing
BP-40229(+)-JQ1 carboxylic acidMolecular structure of the compound: (+)-JQ1 carboxylic acid400.998%Pricing
BP-41900(+)-JQ-1-PEG4-Amine, TFA saltMolecular structure of the compound: (+)-JQ-1-PEG4-Amine, TFA salt619.295%Pricing
BP-41899(+)-JQ-1-PEG4-Amido-N-t-BocMolecular structure of the compound: (+)-JQ-1-PEG4-Amido-N-t-Boc719.395%Pricing
BP-42230KB02-JQ1Molecular structure of the compound: KB02-JQ1796.8Pricing
Beta-NF-JQ1
BP-42184Beta-NF-JQ1Molecular structure of the compound: Beta-NF-JQ1816.4Pricing
dBET1
BP-27851dBET1Molecular structure of the compound: dBET1785.3Pricing
I-BET 762
BP-23442I-BET 762Molecular structure of the compound: I-BET 762423.998%Pricing
MS-436
BP-23376MS-436Molecular structure of the compound: MS-436383.498%Pricing
BI-2536
BP-23384BI-2536Molecular structure of the compound: BI-2536521.795%Pricing
RVX-208
BP-23380RVX-208Molecular structure of the compound: RVX-208370.498%Pricing
BAY 299
BP-25347BAY 299Molecular structure of the compound: BAY 299429.5Pricing
BAZ2-ICR
BP-25348BAZ2-ICRMolecular structure of the compound: BAZ2-ICR357.4Pricing
BI 9564
BP-25349BI 9564Molecular structure of the compound: BI 9564353.4Pricing
Bromosporine
BP-25350BromosporineMolecular structure of the compound: Bromosporine404.5Pricing
CPI 203
BP-25351CPI 203Molecular structure of the compound: CPI 203399.9Pricing
GSK 2801
BP-25352GSK 2801Molecular structure of the compound: GSK 2801371.5Pricing
GSK 5959
BP-25353GSK 5959Molecular structure of the compound: GSK 5959394.5Pricing
GSK 6853
BP-25354GSK 6853Molecular structure of the compound: GSK 6853409.5Pricing
I-BRD9
BP-25356I-BRD9Molecular structure of the compound: I-BRD9497.6Pricing
NI 57
BP-25365NI 57Molecular structure of the compound: NI 57383.4Pricing
OTX 015
BP-25368OTX 015Molecular structure of the compound: OTX 015492Pricing
PFI
BP-25371PFI 1Molecular structure of the compound: PFI 1347.4Pricing
BP-25372PFI 3Molecular structure of the compound: PFI 3321.4Pricing
BP-25373PFI 4Molecular structure of the compound: PFI 4380.5Pricing
SGC-CBP30
BP-25374SGC-CBP30Molecular structure of the compound: SGC-CBP30509.1Pricing
XMD 8-92
BP-25377XMD 8-92Molecular structure of the compound: XMD 8-92474.6Pricing
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
BP-27845N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amineMolecular structure of the compound: N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine505.7Pricing