(Methyltetrazine-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane
(Methyltetrazine-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane is a click chemistry PEG reagent which contains three azide groups and a methyltetrazine group. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. . Please contact us for GMP-grade inquiries.

Product Citations
- Fernández de Santaella Sunyer, J. (2024). High-Throughput Engineering of Human Arginase-1: Integrating Enzymatic Reporter Cascades, Genetic Code Expansion, and Site-Specific Bioconjugation (Doctoral dissertation, ETH Zurich).
https://www.research-collection.ethz.ch/handle/20.500.11850/710487?show=full