Azido-PEG3-Val-Cit-PAB-PNP

Azido-PEG3-Val-Cit-PAB-PNP

Azido-PEG3-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP groupg is a good leaving group when treating with aminebearing payload. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-23368
    • Unit
    • Price
    • Qty
    • 50 MG
    • $750.00
    • 100 MG
    • $1200.00
    • 250 MG
    • $2300.00

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Product Citations

  1. Gonzalez, Paulina, Sashi Debnath, Yu-An Chen, Elizabeth Hernandez, Preeti Jha, Marianna Dakanali, Jer-Tsong Hsieh, and Xiankai Sun. A Theranostic Small-Molecule Prodrug Conjugate for Neuroendocrine Prostate Cancer. Pharaceutics. 2023
    https://www.mdpi.com/1999-4923/15/2/481?trk=organization_guest_main-feed-card-text