DBCO-NHS

DBCO-NHS

DBCO-NHS Ester is a very popular amine-reactive click chemistry reagent. It can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules. DBCO is commonly used for copper-free Click Chemistry reactions. . Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22231
    • Unit
    • Price
    • Qty
    • 100 MG
    • $140.00
    • 250 MG
    • $350.00
    • 500 MG
    • $540.00
    • 1 G
    • $860.00

Usually ships within 24 hours.

Would you like to inquire about custom quantity?
Inquire

Product Citations

  1. Bertucci, A., Capelli, L., Pedrini, F., Di Pede, A. C., Bagheri, N., Fortunati, S., ... & Porchetta, A. (2023). Synthetic Protein-to-DNA Input Exchange for Protease Activity Detection Using CRISPR-Cas12a.
    https://chemrxiv.org/engage/chemrxiv/article-details/6565bf5acf8b3c3cd74f4ffb
  2. Hu, H., & Zhang, C. (2025). Conjugation of Multiple Proteins Onto the Surface of PLGA/Lipid Hybrid Nanoparticles. Journal of Biomedical Materials Research Part A, 113(1), e37807.
    https://doi.org/10.1002/jbm.a.37807