DBCO-amine

DBCO-amine

DBCO-amine is a simple building block containing a DBCO moiety and will add minimal spacer to the modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22066
    • Unit
    • Price
    • Qty
    • 100 MG
    • $280.00
    • 250 MG
    • $560.00
    • 500 MG
    • $927.00
    • 1 G
    • $1419.00

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Product Citations

  1. Lwin, Thinzar M., Megan Minnix, Lin Li, Anakim Sherman, Teresa Hong, Jeffery YC Wong, Tove Olafsen Multimodality PET and Near-Infrared Fluorescence Intraoperative Imaging of CEA-Positive Colorectal Cancer.. Molecular Imaging and Biology. 2023
    https://link.springer.com/article/10.1007/s11307-023-01831-8
  2. Maciej K, Lin L, Supriyo B, et al. Generation of dual specific bivalent BiTEs (dbBIspecific T-cell Engaging antibodies) for cellular immunotherapy.  BMC Cancer. 2019 September; 19 (882).
    https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-019-6056-8
  3. Nakata N, Kobashi N, et al. Radiation dosimetry and efficacy of an 89Zr/225Ac-labeled humanized anti-MUC5AC antibody. Nuclear Medicine and Biology. 2022. 108-109. pp. 33-43.
    https://www.sciencedirect.com/science/article/pii/S0969805122000221